Appendix III: Guide to Case Studies

Chapter 1: Erythrocytes

1. 1. Odie: Relative erythrocytosis due to dehydration (foreign body)
   2. Annie: Anemia of inflammatory disease (pyometra)
   3. Elmo: Anemia due to internal hemorrhage (rodenticide toxicity)
   4. Ricky: Iron deficiency anemia due to chronic external blood loss (intestinal neoplasia)
   5. Pansy: Anemia due to chronic renal disease
   6. Thea: Anemia due to retroviral infection (feline leukemia virus)
   7. Gerda: Anemia due to hypophosphatemic hemolysis
   8. O’Reilly: Anemia due to erythrocyte parasitism (Mycoplasma haemofelis)
   9. Skippy: Anemia due to oxidative injury (Heinz body hemolysis)
   10. 10.Brutus: Anemia due to internal hemorrhage (hemangiosarcoma)
   11. 11.Tonka: Anemia due to immune-mediated hemolysis

Chapter 2: Leukocytes

1. 1. Shirley: Stress leukogram (hypocalcemic cow)
   2. Socks: Acute inflammation and stress (gastroenteritis; bone fragments)
   3. Ranger: Degenerative left shift and stress lymphopenia (large infected laceration)
   4. Harriet: Degenerative left shift (peritonitis?)
   5. Sunny: Left shift (transition) becoming severe neutropenia due to parvoviral infection
   6. Tootsie: Chronic inflammation and stress (chronic pneumonia)
   7. Hailey: Severe inflammation associated with immune-mediated hemolysis
   8. Jimmy: Panleukopenia due to retroviral infection (feline leukemia virus)

Chapter 3: Hemopoietic Neoplasia

1. 1. Micky: Systemic mast cell neoplasia including mastocytemia
   2. Katie: Plasma cell leukemia
   3. Betty: Lymphocytic leukemia (bovine leukemia virus)
   4. Prince: Acute lymphoblastic leukemia
   5. Nickle: Myelomonocytic leukemia?
   6. Feather: B cell lymphosarcoma, leukemia, and monoclonal gammopathy

Chapter 4: Hemostasis

1. 1. Trish: Secondary hemostatic disorder (warfarin-type rodenticide toxicity)
   2. Marble: Primary hemostatic disorder (von Willebrand disease)
   3. Larry: Secondary hemostatic disorder (Factor VIII deficiency/hemophilia A)
   4. Charisse: Primary hemostatic disorder (thrombocytopenia due to bone marrow neoplasia)
   5. Cubby: Primary and secondary hemostatic disorders (disseminated intravascular coagulation and fibrinolysis) due to lymphocytic leukemia and hypercalcemia

Chapter 5: Cytology

1. 1. Chloe: Feline infectious peritonitis
   2. Tundra: Septic exudate (peritonitis)
   3. Danni: Neoplastic effusion (adenocarcinoma)
   4. Kaleb: Hemorrhagic effusion (hemangiosarcoma)
   5. Ginny: Chylous effusion due to chronic bronchitis
   6. Blue: Septic exudate (meningitis) due to trauma
   7. Pierre: Histiocytic sarcoma
   8. Daisy: Osteosarcoma
   9. Skit: Cutaneous histiocytoma
   10. 10.Tex: Transitional cell carcinoma

Chapter 6: Body water, Electrolytes, and Acid-Base Balance

1. 1. Sonata: Hypochloremic metabolic alkalosis secondary to intestinal foreign body
   2. Theodore: Diabetes mellitus and ketoacidosis (high anion gap metabolic acidosis)
   3. Brie: Sample for biochemical analysis collected in EDTA
   4. Nina: Metabolic alkalosis and paradoxic aciduria
   5. Ramona: Grain overload

Chapter 7: Renal System

1. 1. Bill: Acute renal disease (ethylene glycol toxicity)
   2. Hobbes: Renal disease associated with neoplasia (renal lymphosarcoma)
   3. Marina: Pyelonephritis
   4. Phillip: Protein-losing nephropathy
   5. Tyrion: Uroabdomen

Chapter 8: Hepatobiliary System

1. 1. Tess: Intrahepatic shunt
   2. Tigger: Hepatic lipidosis
   3. Jade: Chronic hepatic disease
   4. Charles: Extrahepatic biliary obstruction due to lymphosarcoma
   5. Ferdinand: Cholecystitis and ruptured gall bladder

Chapter 9: Digestive System

1. 1. Pamela: Protein-losing enteropathy ( lymphangiectasia and inflammatory bowel disease)
   2. Josie: Exocrine pancreatic insufficiency
   3. Sonia: Peritonitis and necrotic enteritis
   4. Petra: Hyperlipasemia associated with pancreatic/hepatic neoplasia
   5. Dirk: Canine pancreatitis

Chapter 10: Endocrine System

1. 1. Jolene: Hyperadrenocorticism
   2. Spock: Insulinoma
   3. Gavino: Equine pituitary pars intermedia dysfunction
   4. Malika: Hyperthyroidism
   5. Marigold: Hypothyroidism
   6. Marly: Hypoadrenocorticism

Chapter 11: Muscle

1. 1. Petunia: Postparturient hypocalcemia
   2. Nevada: Polysaccharide storage myopathy

Chapter 12: Proteins

1. 1. Dolly: Pleuropneumonia
   2. Zed: Chronic inflammation

Chapter 13: Lipids

1. 1. Frederick: Primary idiopathic hyperlipidemia
   2. Gale: Hyperlipidemia secondary to anorexia

Appendix I:Practice Cases

1. 1. Katarina: Hypercalcemia-granulomatous disease
   2. Thor: Hypoadrenocorticism
   3. Wally: Aortic thromboembolism
   4. Ronaldo: Primary hyperparathyroidism
   5. Dan: Inflammation, hemoconcentration, electrolyte disturbances related to diarrhea
   6. Zack: Septicemia and chronic renal disease
   7. Sauron: PFK deficiency